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L1294

Lactoferrin human

recombinant, expressed in rice, Iron saturated, ≥90% (SDS-PAGE)

Synonim(y):

Holo Transferrin

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Rozmiar/SKUDostępnośćCena netto
100 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
931,00 zł
1 g
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4770,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
Form:
powder
Assay:
≥90% (SDS-PAGE), ≥90% (biuret)
Biological source:
human
Recombinant:
expressed in rice

931,00 zł


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biological source

human

Quality Segment

recombinant

expressed in rice

type

for cell culture

assay

≥90% (SDS-PAGE), ≥90% (biuret)

form

powder

technique(s)

microbiological culture: suitable

impurities

≤10 EU/mg endotoxin

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... LTF(4057)

Application

Lactoferrin was used to grow Streptococcus mutans in an iron-limiting medium. It was used to test if lactoferrin impedes epithelial cell adhesion in vitro.

Biochem/physiol Actions

Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.

Other Notes

rhLactoferrin manufactured in the USA by InVitria.
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Ta pozycja
L404061327L3770
description

recombinant, expressed in rice, Iron saturated, ≥90% (SDS-PAGE)

description

recombinant, expressed in rice, Partially iron saturated, ≥90% (SDS-PAGE)

description

iron-saturated, ≥85% (GE)

description

Iron saturated, ≥85% (SDS-PAGE)

recombinant

expressed in rice

recombinant

expressed in rice

recombinant

-

recombinant

-

biological source

human

biological source

human

biological source

human milk

biological source

human milk

technique(s)

microbiological culture: suitable

technique(s)

microbiological culture: suitable

technique(s)

-

technique(s)

microbiological culture: suitable

assay

≥90% (SDS-PAGE), ≥90% (biuret)

assay

≥70% protein basis (Bradford), ≥90% (SDS-PAGE)

assay

≥85% (GE)

assay

≥85% (SDS-PAGE)

form

powder

form

powder

form

solid

form

powder

impurities

≤10 EU/mg endotoxin

impurities

-

impurities

-

impurities

-


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Klasa składowania

11 - Combustible Solids

Co się dzieje?

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

PPE (środki ochrony indywidualnej)

Eyeshields, Gloves, type N95 (US)



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  
  1. what is the molecular weight of L1294, Lactoferrin human?

    1 answer
    1. The molecular weight of this product is approximately 80 kDa.

      Helpful?

  2. Do you have a recommendation for storage after dissolving in H2O? I cannot find any handling instructions online.

    1 answer
    1. The stability of this item has not been tested once it is in solution. It is recommended to make fresh before using the item.

      Helpful?

  3. What is the sequence of this product? Do you have the half (1-11) peptide product?

    1 answer
    1. L1294, Lactoferrin human, has the exact same amino acid sequence as the native protein. Unfortunately, we do not supply human lactoferrin peptide hLF1-11.

      Helpful?

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