T8158

Transferrin human

powder, BioReagent, suitable for cell culture

• Synonim(y): Siderophilin, partially saturated
• Numer CAS: 11096-37-0
• Numer WE: 234-318-8
• Numer MDL: MFCD00132442
• Kod UNSPSC: 12352202
• NACRES: NA.75

Właściwości

• linia produktu: BioReagent
• Próba: ≥98%
• Postać: powder
• stężenie: ~25 mM
• metody: cell culture | mammalian: suitable
• zanieczyszczenia: endotoxin, tested; hepatitis and HIV antibody, none detected
• rozpuszczalność: H₂O: 50 mg/mL
• numer dostępu UniProt: P02787
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• informacje o genach: human ... TF(7018)

Opis

Opis ogólny

Transferrin is a glycoprotein with a branched carbohydrate chain, having two sites for ferric ion binding in its polypeptide chain.

Zastosowanie

Transferrin human has been used:

• to incubate human proximal tubule cells (HKC) - 8 cells along with IgG for the examination of albumin specificity
• as a supplement in serum-containing/devoid medium for human thyroid cell culture
• as a target glycoprotein to develop an in-gel hydrazinolysis method

Działania biochem./fizjol.

Transferrin mediates iron transportation from plasma to cells. The iron-bound transferrin are of three forms: monoferric A/B transferrin and diferric transferrin. The transferrin binds to specific cell surface receptors and are internalized by endocytosis. Once inside, the iron is released into the cells and the iron-free transferrin, also referred to as apotransferrin, is exocytosed outside the cell without being degraded. Transferrin is known to deliver iron to cells in a physiologically safe and effective form.

Inne uwagi

Partially iron-saturated

Uwaga dotycząca przygotowania

Heat treated at 60 °C for ten hours.

Komentarz do analizy

Purity by agarose electrophoresis.

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable