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L9507

Lactoferrin from bovine milk

≥85% (SDS-PAGE)

Synonim(y):

Bos d LF, Lactotransferrin

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Do Państwa/SKUDostępnośćCena netto
10 mg
Skontaktuj się z Obsługą Klienta, aby uzyskać informacje na temat dostępności
471,00 zł
50 mg
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1640,00 zł

Informacje o tej pozycji

Numer CAS:
936541-36-5
UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:
MFCD00131481
Form:
powder
Assay:
≥85% (SDS-PAGE)
Biological source:
bovine milk
Mol wt:
~87 kDa

471,00 zł

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biological source

bovine milk

Quality Segment

200

assay

≥85% (SDS-PAGE)

form

powder

mol wt

~87 kDa

technique(s)

fractionation: suitable

solubility

H2O: soluble 10 mg/mL

UniProt accession no.

P24627

storage temp.

2-8°C

Gene Information

cow ... LTF(280846)

Application

Lactoferrin was used in the fractionation of lactoperoxidase and lactoferrin from bovine whey using a cation exchange membrane. It was used in the determination of lactoferrin and immunoglobulin G in animal milks by new immunosensors.[1]

Biochem/physiol Actions

Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.
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L052061327L4894
Lactoferrin from bovine milk ≥85% (SDS-PAGE)

Sigma-Aldrich

L9507

Lactoferrin from bovine milk

Lactoferrin from human milk ≥85% (SDS-PAGE), lyophilized powder

Sigma-Aldrich

L0520

Lactoferrin from human milk

Lactoferrin from human milk iron-saturated, ≥85% (GE)

Sigma-Aldrich

61327

Lactoferrin from human milk

Lactoferrin from human milk powder, BioReagent, suitable for cell culture

Sigma-Aldrich

L4894

Lactoferrin from human milk

assay

≥85% (SDS-PAGE)

assay

≥85% (SDS-PAGE)

assay

≥85% (GE)

assay

≥85% (SDS-PAGE)

biological source

bovine milk

biological source

human milk

biological source

human milk

biological source

-

technique(s)

fractionation: suitable

technique(s)

microbiological culture: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

form

powder

form

lyophilized powder

form

solid

form

powder

mol wt

~87 kDa

mol wt

82.4 kDa

mol wt

82.4 kDa

mol wt

82.4 kDa

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. Is this product dissolvable in plant based oils?

    1 answer

    1. This product has not been tested for solubility in plant oils. However, it can be solubilized in water and aqueous solutions, 10 mg/mL of water and 1 mg/mL of PBS, respectively. A brief search of the literature shows that oil emulsions have been frequently studied.

      See the link below for a publication that may be helpful.
      https://pubs.acs.org/doi/full/10.1021/jf9809939

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