H2779
HistoChoice® Clearing Agent
alternative to toluene and xylene
Synonim(y):
dewaxing mixture for paraffin tissue sections
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About This Item
Kod UNSPSC:
12171500
NACRES:
NA.47
Polecane produkty
Postać
liquid
charakterystyka ekologicznej alternatywy
Designing Safer Chemicals
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sustainability
Greener Alternative Product
kolor
colorless
gęstość
0.760-0.820 g/mL
Zastosowanie
hematology
histology
kategoria ekologicznej alternatywy
, Aligned
temp. przechowywania
room temp
Opis ogólny
HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
Zastosowanie
HistoChoice® Clearing Agent has the following applications:
- It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
- It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
- It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
- It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.
Działania biochem./fizjol.
Fixation with HistoChoice® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.
Cechy i korzyści
- Non-toxic, non-carcinogenic, and odorless.
- Non-flammable.
- Preserves native antigenic and nucleic acid sites.
- Compatible with many organic mounting media.
- Dissolves wax faster and evaporates slower than xylene.
- Can be used in automated processors.
- Tissues retain their original structure.
Informacje prawne
HistoChoice is a registered trademark of Amresco, Inc.
Hasło ostrzegawcze
Warning
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organy docelowe
Respiratory system
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
142.0 °F
Temperatura zapłonu (°C)
61.1 °C
Środki ochrony indywidualnej
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Certyfikaty analizy (CoA)
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Marie-Françoise Devaux et al.
Frontiers in plant science, 9, 200-200 (2018-03-09)
Tracking enzyme localization and following the local biochemical modification of the substrate should help explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation. Time-lapse studies using conventional imaging require enzyme labeling and following the biochemical modifications of biopolymers
Anita S Patel et al.
The Journal of investigative dermatology, 128(12), 2888-2893 (2008-06-13)
An increasing number of studies report that genus beta human papillomaviruses (HPVs) are associated with skin cancer, with suggestions of specificity for squamous cell carcinoma (SCC) of the skin. We have conducted a systematic examination of HPV DNA in tumors
Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers
Aimi, et al.
Modern Pathology (2021)
Sathyanesan Samuel Newton et al.
Brain research. Brain research protocols, 9(3), 214-219 (2002-07-13)
A method is described to perform combined immunohistochemistry and in situ hybridization in mouse brain sections. The protocol is specific to sections mounted on glass slides. In contrast to earlier methods that require either paraffin embedding or perfusion of the
Synchrotron Time-Lapse Imaging of Lignocellulosic Biomass Hydrolysis: Tracking Enzyme Localization by Protein Autofluorescence and Biochemical Modification of Cell Walls by Microfluidic Infrared Microspectroscopy
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Powiązane treści
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