F8775

Formaldehyde solution

for molecular biology, 36.5-38% in H₂O

• Synonim(y): Formalin
• Wzór liniowy: HCHO
• Numer CAS: 50-00-0
• Masa cząsteczkowa: 30.03
• Beilstein: 1209228
• Numer WE: 200-001-8
• Numer MDL: MFCD00003274
• Kod UNSPSC: 12352114
• Identyfikator substancji w PubChem: 24894976
• NACRES: NA.31
• klasa czystości: for molecular biology
• metody: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry: suitable
• Zastosowanie: general analytical; genomic analysis
• ciśnienie pary: 52 mmHg ( 37 °C)

Właściwości

• klasa czystości: for molecular biology
• Poziom jakości: 100
• gęstość pary: 1.03 (vs air)
• ciśnienie pary: 52 mmHg ( 37 °C)
• Formularz: liquid
• temp. samozapłonu: 572 °F
• zawiera: 10-15% methanol
• stężenie: 36.5-38% in H₂O
• metody: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry: suitable
• gęstość: 1.09 g/mL at 25 °C (lit.)
• przydatność: suitable for (use in Formaldehyde-Agarose Gel Electrophoresis of RNA)
• Zastosowanie: general analytical; genomic analysis
• temp. przechowywania: 15-25°C
• ciąg SMILES: [H]C([H])=O
• InChI: 1S/CH2O/c1-2/h1H2
• Klucz InChI: WSFSSNUMVMOOMR-UHFFFAOYSA-N

Opis

Opis ogólny

Formaldehyde, a colorless, pungent-smelling chemical, finds extensive application in various biological research and laboratory settings. Primarily supplied as a 37% solution (formalin), its diverse uses range from tissue preservation and sterilization to acting as a denaturant in RNA gel electrophoresis. However, it′s crucial to acknowledge its potential health risks and handle it with appropriate precautions.Multifaceted Functions:

• Preservative: Formaldehyde′s ability to inhibit microbial growth makes it an effective preservative in biological samples, preventing decay and ensuring their integrity for further analysis. This property finds application in medical laboratories, museums, and even embalming fluids.
• Fixative: In histology, formaldehyde acts as a fixative, cross-linking proteins and preserving tissue structures for microscopic examination. This allows researchers to visualize anatomical details and cellular components with remarkable clarity.
• Denaturant: In molecular biology techniques like formaldehyde-agarose gel electrophoresis, formaldehyde denatures RNA molecules, preventing them from forming secondary structures and enabling size-based separation. This technique proves invaluable for studying gene expression and RNA integrity.

Zastosowanie

Formaldehyde solution has been used for fixing of cells and tissue sections.[1][2] It has been used in the formaldehyde agarose gel electrophoresis.[3] Formaldehyde is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA.

Cechy i korzyści

• Versatile and adaptable for a wide variety of laboratory and research applications
• Suitable for Molecular Biology and Biochemical applications

Komentarz do analizy

Tested for use in formaldehyde-agarose gel electrophoresis of RNA.

Inne uwagi

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS08,GHS05
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H226,H301 + H311,H314,H317,H330,H335,H341,H350,H370
• Zwroty wskazujące środki ostrożności: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3
• Organy docelowe: Eyes,Central nervous system, Respiratory system
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): 133.0 °F - closed cup
• Temperatura zapłonu (°C): 56.11 °C - closed cup