H0916
Anti-HOXA10 (N-terminal) antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
Synonim(y):
Anti-HOMEOBOX 1H, Anti-HOMEOBOX A10, Anti-HOX-1.8, Anti-HOX1H
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About This Item
Kod UNSPSC:
12352203
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
rabbit
białko sprzężone
unconjugated
forma przeciwciała
affinity isolated antibody
rodzaj przeciwciała
primary antibodies
klon
polyclonal
Postać
buffered aqueous solution
masa cząsteczkowa
antigen ~50 kDa
reaktywność gatunkowa
human
stężenie
~1.0 mg/mL
metody
western blot: 1-2 μg/mL using lysates of HEK-293T cells over expressing human HOXA10
numer dostępu UniProt
Warunki transportu
dry ice
temp. przechowywania
−20°C
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... HOXA10(3206)
Opis ogólny
The homeobox A10 (HOXA10) protein is localized in the adult human endometrium. The HOXA10 gene is mapped on the human chromosome at 7p15.2.
Specyficzność
Anti-HOXA10 (N-terminal) recognizes human HOXA10 (also known as Hox-1H and HOX-1).
Zastosowanie
Anti-HOXA10 (N-terminal) antibody produced in rabbit has been used in immunoblotting.
Działania biochem./fizjol.
Homeobox A10 (HOXA10) protein is critical for the normal development of the erythroid and megakaryocytic lineages. The expression of the HOXA10 gene was found to be altered in endometriosis. HOXA10 protein plays a role in mediating endometrial development during the menstrual cycle. This protein is also involved in preparing the endometrium for implantation in humans.
Postać fizyczna
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Przechowywanie i stabilność
For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Certyfikaty analizy (CoA)
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Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Alysson Zanatta et al.
Journal of assisted reproduction and genetics, 27(12), 701-710 (2010-09-08)
endometriosis and its associated infertility have been the object of continuous research for over a century. To understand the molecular mechanisms underlying the disease, it has become necessary to determine the aspects of its etiology that are not explained by
J Julie Kim et al.
Molecular human reproduction, 13(5), 323-332 (2007-03-14)
Endometriosis is a poorly understood gynaecologic disorder that is associated with infertility. In this study, we examined the expression of HOXA10 in the eutopic endometrium of baboons with induced endometriosis. A decrease in HOXA10 mRNA was observed after 3, 6
H S Taylor et al.
The Journal of clinical investigation, 101(7), 1379-1384 (1998-04-29)
Hox genes are well-known transcriptional regulators that play an essential role in directing embryonic development. Mice that are homozygous for a targeted disruption of the Hoxa10 gene exhibit uterine factor infertility. We have recently demonstrated that HOXA10 is expressed in
Nan Zhu et al.
The Journal of clinical investigation, 126(3), 997-1011 (2016-02-16)
Self-renewal is a hallmark of both hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs); therefore, the identification of mechanisms that are required for LSC, but not HSC, function could provide therapeutic opportunities that are more effective and less toxic
Edward J Richards et al.
Oncotarget, 6(33), 34745-34757 (2015-10-03)
The homeobox A (HOXA) region of protein-coding genes impacts female reproductive system embryogenesis and ovarian carcinogenesis. The 5-prime end of HOXA includes three long non-coding RNAs (lncRNAs) (HOXA10-AS, HOXA11-AS, and HOTTIP) that are underexplored in epithelial ovarian cancer (EOC). We
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