Monascin is one of the major yellow pigments found in red mold rice. It is structurally similar to ankaflavin.
Zastosowanie
Monascin has been used to treat 4T1 breast cancer cells and to test its effects on tumor cells anoikis and growth prevention.
Działania biochem./fizjol.
Monascin (MS) exerts anti-diabetic and antioxidant properties and provides hyperglycemia control, tissue protection, and thermotolerance in diabetic rats and C. elegans, respectively. It also displays antitumor activity and inhibits Alzheimer′s disease-related tau protein aggregation. Monascin up-regulates high-density lipoprotein cholesterol (HDL-C) levels in hyperlipidemic hamsters model and possesses hypolipidemic properties. It may also possess hepatoprotective effects.
Monascin is one of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mold rice). It is a potent inhibitor of carcinogenesis measured against chemical or UV initiated, phorbol-promoted mouse skin tumors.
Opakowanie
Bottomless glass bottle. Contents are inside inserted fused cone.
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We examined the effect of various carbohydrates on the proliferative response of murine thymocytes to cytokines. The monosaccharide, D-mannose (4-10 mM), significantly inhibited thymocyte proliferation induced by recombinant interleukin-1 (rIL-1). Mannose also inhibited the proliferation response to native, human IL-1.
Journal of agricultural and food chemistry, 58(16), 9013-9019 (2010-07-30)
Monascus-fermented red mold dioscorea (RMD) has been proven to possess greater hypolipidemic effect than red mold rice (RMR) even though they include equal levels of cholesterol-lowering agent monacolin K. However, higher concentrations of yellow pigments (monascin and ankaflavin) were found
[Symposium "Mechanisms of allergic inflammation". 2d Meeting of the Professional Society of the ADF: Immunologic mechanisms of inflammatory skin diseases. 21-23 February 1992, Freiburg i. Br].
W Czech
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 43(11), 743-744 (1992-11-01)
Monascin is a major yellow compound from red mold dioscorea. We investigated monascin to test whether this compound acts as an antidiabetic and antioxidative stress agent in diabetic rats and Caenorhabditis elegans. The mechanisms by which monascin exerts its action
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