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Y0001171

Astragaloside IV

European Pharmacopoeia (EP) Reference Standard

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About This Item

Wzór empiryczny (zapis Hilla):
C41H68O14
Numer CAS:
84687-43-4
Masa cząsteczkowa:
784.97
Numer MDL:
MFCD16036240
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329831290
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

astragaloside

producent / nazwa handlowa

EDQM

mp

295-296 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

ciąg SMILES

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

Klucz InChI

QMNWISYXSJWHRY-YLNUDOOFSA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Astragaloside IV EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Działania biochem./fizjol.

Anti-inflammatory.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
This page may contain text that has been machine translated.

produkt powiązany

Numer produktu
Opis
Cennik

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Choose from one of the most recent versions:

Certyfikaty analizy (CoA)

Lot/Batch Number

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Sigma-Aldrich

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Sigma-Aldrich

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Shuang Ren et al.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 33(3), 413-416 (2013-09-13)
To review the pharmacological effects and mechanisms of action of Astragaloside IV in Huangqi (Radix Astragali Mongolici). Aticles focusing on Astragaloside IV in English and Chinese in databases were collected and reviewed in order to summarize the latest extraction separation
Jing Zhang et al.
FEMS microbiology letters, 367(4) (2020-02-29)
Excessive secretion of inflammatory factors (cytokine storm) plays a significant role in H1N1-induced acute pneumonia, and autophagy acts as a cell-intrinsic mechanism to regulate inflammation. Astragaloside IV (AS-IV), originating from the astragalus root, possesses multiple pharmacological activities, such as anti-inflammation.
Feng Liu et al.
Archivum immunologiae et therapiae experimentalis, 68(6), 33-33 (2020-10-24)
Astragaloside IV (AS-IV) has shown anti-tumorigenic properties in certain cancers for its effect of boosting the body's immune system, but its role in colorectal cancer (CRC) remains unclear. In this study, we investigated the therapeutic effect of AS-IV in CRC
Biwang Liu et al.
Pharmacology, 105(1-2), 90-101 (2019-09-26)
Astragaloside IV has shown its promising effect on acute respiratory distress syndrome (ARDS). We aim to explore whether astragaloside IV is effective for ARDS treatment in a lipopolysaccharides (LPS)-induced cell model and whether autophagy is involved in the therapeutic function
Li Wang et al.
Experimental biology and medicine (Maywood, N.J.), 239(10), 1310-1324 (2014-06-01)
Astragaloside IV (AS-IV) is a major active ingredient from Radix astragali, which has been considered as a renoprotective agent; however, its molecular mechanisms are unclear. Thus, we designed to investigate the renoprotective effects and mechanisms of AS-IV in rat model

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