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S2002

Sodium azide

ReagentPlus®, ≥99.5%

Sodium azide

Synonim(y):

Hydrazoic acid sodium salt

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Gabaryty przesyłkiSKUDostępnośćCena netto
5 g
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108,00 zł
25 g
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226,00 zł
100 g
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436,00 zł
500 g
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952,00 zł
2 kg
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3630,00 zł

Informacje o tej pozycji

Wzór liniowy:
NaN3
Numer CAS:
Masa cząsteczkowa:
65.01
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
247-852-1
MDL number:

108,00 zł


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biological source

synthetic (inorganic)

Quality Segment

product line

ReagentPlus®

assay

≥99.5%

form

powder

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)

technique(s)

cell based assay: suitable, immunohistochemistry: suitable

color

white

mp

370-425 °C

solubility

soluble 65 g/L at 20 °C (completely)

suitability

suitable for chromatography, suitable for derivatization

application(s)

sample preparation

SMILES string

[Na]N=[N+]=[N-]

InChI

1S/N3.Na/c1-3-2;/q-1;+1

InChI key

PXIPVTKHYLBLMZ-UHFFFAOYSA-N

General description

Sodium Azide (NaN3) is a potent inhibitor – a water-soluble crystalline powder that′s odorless. Widely recognized for its versatile applications, it plays a pivotal role across molecular biology, cell culture, and biochemical research. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation. In cell culture, it maintains the integrity of your cell lines.

Application

Sodium azide is suitable for use in histopathology to prepare and store tissue samples.[1] [2] Also used as a component of staining buffer (HEPES buffer) for whole mount immunolabelling.
Catalyst for:

  • Oxidative decarboxylation
  • Michael addition reactions[3]

Reagent for synthesis of
  • Blue fluorescent copolymers
  • Metal phosphonates[4]
  • Arenes via aminations
Baylis-Hillman acetates such as ethyl 2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.

Biochem/physiol Actions

It prevents capping and internalization of fluorescent surface-bound antibodies in various scientific applications, including flow cytometry.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
1.066887129071289
biological source

synthetic (inorganic)

biological source

-

biological source

-

biological source

-

assay

≥99.5%

assay

-

assay

≥99.0% (T)

assay

≥99.5% (T)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

-

form

crystals

form

crystals

solubility

soluble 65 g/L at 20 °C (completely)

solubility

420 g/L

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)

storage condition

-

storage condition

-

storage condition

-


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Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

target_organs

Brain

supp_hazards

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protokoły

Protokoły oczyszczania przeciwciał dają preparaty zawierające endogenne IgG wraz ze specyficznymi przeciwciałami.

Detailed ELISA protocols cover indirect and capture ELISA techniques, recommending products for sandwich and indirect ELISA experiments.

Szczegółowe protokoły ELISA obejmują pośrednie i wychwytujące techniki ELISA, zalecając produkty do eksperymentów kanapkowych i pośrednich ELISA.

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Powiązane treści


A critical review of published methods for analysis of red cell antigen-antibody reactions by flow cytometry, and approaches for resolving problems with red cell agglutination
Patricia A Arndt , George Garratty
Transfusion Medicine Reviews, 24(3), 174-192 (2010)
Sodium azide, a bacteriostatic preservative contained in commercially available laboratory reagents, influences the responses of human platelets via the cGMP/PKG/VASP pathway.
Russo I, et al.
Clinical Biochemistry, 41(4), 343-349 (2008)
Nucleophilic displacement by azide and cyanide on Baylis-Hillman acetates in water.
Yadav JS, et al.
Tetrahedron Letters, 46(16), 2761-2763 (2005)



Numer pozycji handlu globalnego

SKUNUMER GTIN
S2002-2KG04061836916053
S2002-25KG04061833512913
S2002-500G04061835549306
S2002-25G04061835549290
S2002-100G04061835549283
S2002-5G04061835549313

Questions

1–8 of 8 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. what do you mean by Bioxtra and reagentplus? How much difference are there between two grades.

    1 answer
    1. Products that fall under the BioXtra portfolio undergo stringent testing protocols that may include trace metal analysis and specialized suitability testing, such as hybridoma or mouse embryo culture. These products include application-specific formulations such as tablets and prepared solutions.

      Products that fall under the ReagentPlus portfolio are designed for general laboratory use and have purities that are greater or equal to 95%.

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  4. How can I determine the concentration of sodium azide in solution?

    1 answer
    1. Sodium azide forms a 3,5-dinitrobenzoyl derivative that can be quantified by liquid chromatography.  This method is reported in the Journal of Chromatography, 5, 597 (1982).

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  5. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  6. How does Product S2002, Sodium azide, inhibit certain metalloenzymes?

    1 answer
    1. The mechanism of sodium azide inhibition may be due to metal ion complexation and displacement from the enzyme.

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  7. Are there any hazards associated with the disposal of Product S2002, Sodium azide?

    1 answer
    1. Sodium azide can form metal azides.  If you have metal pipes for your plumbing, you should not dispose of solutions down them.

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  8. How stable are solutions of Product S2002, Sodium azide?

    1 answer
    1. At a neutral pH sodium azide solutions are fairly stable.  Under acidic conditions it is converted to hydrazoic acid, a volatile gas.

      Helpful?

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