PHR1366

Dibutyl Phthalate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Dibutyl phthalate, n-Butyl phthalate, DBP, Phthalic acid dibutyl ester
• Wzór liniowy: C₆H₄-1,2-[CO₂(CH₂)₃CH₃]₂
• Numer CAS: 84-74-2
• Masa cząsteczkowa: 278.34
• Beilstein: 1914064
• Numer WE: 201-557-4
• Numer MDL: MFCD00009441
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329823345
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to Ph. Eur. D1010000; traceable to USP 1187080
• gęstość pary: 9.6 (vs air)
• ciśnienie pary: 1 mmHg ( 147 °C)
• rodzina API: dibutyl phthalate
• Certyfikat analizy: current certificate can be downloaded
• temp. samozapłonu: 756 °F
• granice wybuchowości: 0.47 %, 236 °F
• opakowanie: pkg of 1 g
• metody: HPLC: suitable; gas chromatography (GC): suitable
• współczynnik refrakcji: n20/D 1.492 (lit.)
• bp: 340 °C (lit.)
• mp: −35 °C (lit.)
• gęstość: 1.043 g/mL at 25 °C (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• Format: neat
• temp. przechowywania: 2-30°C
• ciąg SMILES: CCCCOC(=O)c1ccccc1C(=O)OCCCC
• InChI: 1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
• Klucz InChI: DOIRQSBPFJWKBE-UHFFFAOYSA-N

Opis

Opis ogólny

Dibutyl Phthalate is a diester of phthalate, commonly synthesized by the condensation of the carboxy groups of phthalic acid with two molecules of 1-butanol.[1] It is used as a plasticizer and film coating agent in solid pharmaceutical dosage forms.[2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Plastyfikator

Dibutyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and dietary supplements by chromatography.[2][3][4]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAA1470 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS09
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H360FD,H410
• Zwroty wskazujące środki ostrożności: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Klasyfikacja zagrożeń: Aquatic Acute 1 - Aquatic Chronic 2 - Repr. 1B
• Kod klasy składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): 339.8 °F
• Temperatura zapłonu (°C): 171 °C