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Merck

PHR1081

Supelco

Octisalate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonim(y):

2-Ethylhexyl salicylate, Octisalate, Octyl salicylate

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About This Item

Wzór liniowy:
(HO)C6H4CO2CH2CH(C2H5)(CH2)3CH3
Numer CAS:
Masa cząsteczkowa:
250.33
Beilstein:
2730664
Numer WE:
Numer MDL:
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
NACRES:
NA.24

klasa czystości

certified reference material
pharmaceutical secondary standard

Poziom jakości

agency

traceable to USP 1477943

rodzina API

octisalate

Certyfikat analizy

current certificate can be downloaded

metody

HPLC: suitable
gas chromatography (GC): suitable

współczynnik refrakcji

n20/D 1.502 (lit.)

tw

189-190 °C/21 mmHg (lit.)

gęstość

1.014 g/mL at 25 °C (lit.)

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-30°C

ciąg SMILES

CCCCC(CC)COC(=O)c1ccccc1O

InChI

1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3

Klucz InChI

FMRHJJZUHUTGKE-UHFFFAOYSA-N

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Opis ogólny

Octisalate is a sunscreen agent that acts as a UV filter for UVB (280-315 nm) radiation.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Octisalate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical and sunscreen formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAC0298 in the slot below. This is an example certificate only and may not be the lot that you receive.
This page may contain text that has been machine translated.

produkt powiązany

Piktogramy

Environment

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Aquatic Chronic 1

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

323.6 °F - closed cup

Temperatura zapłonu (°C)

162 °C - closed cup


Choose from one of the most recent versions:

Certyfikaty analizy (CoA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Thin layer chromatography-spray mass spectrometry: a method for easy identification of synthesis products and UV filters from TLC aluminum foils
Himmelsbach M, et al.
Analytical and Bioanalytical Chemistry, 406(15), 3647-3656 (2014)
Octisalate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 43(3), 3194-3194 (2018)
Development and Validation of RP-HPLC Method for Analysis of Four UV Filters in Sunscreen Products
Yousef AN, et al.
International Journal of Pharmaceutical Sciences Review and Research (2013)
M McVean et al.
Molecular carcinogenesis, 24(3), 169-176 (1999-04-16)
Topical application of alpha-tocopherol (alphaTH), the most prominent naturally occurring form of vitamin E, inhibits ultraviolet (UV) B-induced photocarcinogenesis and DNA photodamage in C3H mice in vivo. In this study, we compared alphaTH with other vitamin E compounds and with
Beatriz Albero et al.
Journal of chromatography. A, 1248, 9-17 (2012-06-12)
The determination of organic contaminants in soil is a real challenge due to the large number of these compounds with quite different physico-chemical properties. In the present work, an analytical method was developed for the simultaneous determination in soil of

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