N0600000

Nicotinamide

European Pharmacopoeia (EP) Reference Standard

• Synonim(y): Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B₃, Vitamin PP
• Wzór empiryczny (zapis Hilla): C₆H₆N₂O
• Numer CAS: 98-92-0
• Masa cząsteczkowa: 122.12
• Beilstein: 383619
• Numer MDL: MFCD00006395
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329818447
• NACRES: NA.24

Właściwości

• pochodzenie biologiczne: synthetic
• klasa czystości: pharmaceutical primary standard
• rodzina API: nicotinamide
• Postać: solid
• producent / nazwa handlowa: EDQM
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 128-131 °C (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• Klucz InChI: DFPAKSUCGFBDDF-UHFFFAOYSA-N

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B₃). It is available in food products and is utilized for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also known for its anti-inflammatory activity.

Zastosowanie

Nicotinamide can be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.

Działania biochem./fizjol.

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H319
• Zwroty wskazujące środki ostrożności: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Klasyfikacja zagrożeń: Eye Irrit. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 302.0 °F - closed cup
• Temperatura zapłonu (°C): 150 °C - closed cup