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92574

Supelco

Mefenamic acid

analytical standard

Synonim(y):

2-[(2,3-Dimethylphenyl)amino]benzoic acid, N-(2,3-Xylyl)anthranilic acid

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About This Item

Wzór empiryczny (zapis Hilla):
C15H15NO2
Numer CAS:
61-68-7
Masa cząsteczkowa:
241.29
Numer WE:
200-513-1
Numer MDL:
MFCD00051721
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329770141
NACRES:
NA.24

klasa czystości

analytical standard

Poziom jakości

100

Próba

≥98.5% (HPLC)

okres trwałości

limited shelf life, expiry date on the label

metody

HPLC: suitable
gas chromatography (GC): suitable

zanieczyszczenia

≤1.0% water

Zastosowanie

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

ciąg SMILES

Cc1cccc(Nc2ccccc2C(O)=O)c1C

InChI

1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)

Klucz InChI

HYYBABOKPJLUIN-UHFFFAOYSA-N

informacje o genach

human ... PTGS1(5742) , PTGS2(5743)

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Zastosowanie

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
An NSAID. Circumvents MRP-mediated multidrug resistance. Specifically and significantly potentiates the cytotoxicity of anthracyclines as well as teniposide, VP-16 and vincristine.
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Piktogramy

Exclamation mark
GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H302

Klasyfikacja zagrożeń

Acute Tox. 4 Oral

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number
BCCK0387
BCCG7671
BCCD0183
BCBW8340
BCBS3985V

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Journal of environmental management, 167, 206-213 (2015-12-22)
Mefenamic acid (MEF) is a non-steroidal anti-inflammatory drug indicated for relief of mild to moderate pain, and for the treatment of primary dysmenorrhea. The presence of MEF in raw and sewage waters has been detected worldwide at concentrations exceeding the
Umang V Shah et al.
International journal of pharmaceutics, 472(1-2), 140-147 (2014-06-15)
The role of surface properties, influenced by particle processing, in particle-particle interactions (powder cohesion) is investigated in this study. Wetting behaviour of mefenamic acid was found to be anisotropic by sessile drop contact angle measurements on macroscopic (>1cm) single crystals
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The Cochrane database of systematic reviews, (3)(3), CD007553-CD007553 (2011-03-18)
Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). It is most often used for treating pain of dysmenorrhoea in the short term (seven days or less), as well as mild to moderate pain including headache, dental pain, postoperative and postpartum
Harini Venkataraman et al.
Bioorganic & medicinal chemistry, 22(20), 5613-5620 (2014-07-08)
Cytochrome P450 BM3 mutants are promising biocatalysts for the production of drug metabolites. In the present study, the ability of cytochrome P450 BM3 mutants to produce oxidative metabolites of structurally related NSAIDs meclofenamic acid, mefenamic acid and tolfenamic acid was
C Reichert et al.
Clinical toxicology (Philadelphia, Pa.), 52(6), 629-634 (2014-05-23)
Seizures during intoxications with pharmaceuticals are a well-known complication. However, only a few studies report on drugs commonly involved and calculate the seizure potential of these drugs. To identify the pharmaceutical drugs most commonly associated with seizures after single-agent overdose
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