MABT84

Anti-Aggrecan Antibody, clone 1-C-6

clone 1-C-6, from mouse

• Synonim(y): Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: 1-C-6, monoclonal
• reaktywność gatunkowa: mouse, rat, bovine
• metody: immunohistochemistry: suitable; western blot: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_071526
• numer dostępu UniProt: P07897
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... ACAN(176)

Opis

Opis ogólny

Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight.

Immunogen

Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma

Zastosowanie

This Anti-Aggrecan Antibody, clone 1-C-6 is validated for use in IH, WB for the detection of Aggrecan.

Western Blot Analysis: 1 µg/mL from a representative lot detected Aggrecan on 10 µg of A1D4 protein fraction from Bovine tissue.

Jakość

Evaluated by Immunohistochemistry in normal mouse cartilage and normal rat cartilage tissues.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues.

Opis wartości docelowych

Various

Postać fizyczna

Format: Purified

Komentarz do analizy

Control
Normal mouse cartilage and normal rat cartilage tissues

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable