09-230

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: canine, human
• reaktywność gatunkowa (przewidywana na podstawie homologii): horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)
• metody: dot blot: suitable; western blot: suitable
• numer dostępu NCBI: NP_065812
• numer dostępu UniProt: Q8N122
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: phosphorylation (pThr706)
• informacje o genach: bovine ... Rptor(507056) ; human ... RPTOR(57521)

Opis

Opis ogólny

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.

Specyficzność

This antibody recognizes Raptor phosphorylated at Thr706.

Immunogen

Epitope: Ser706

KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Zastosowanie

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Jakość

Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Opis wartości docelowych

~ 150 kDa

Postać fizyczna

Purified rabbit serum in PBS with 0.05% sodium azide.

Komentarz do analizy

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable