RPTOR
regulatory associated protein of MTOR, complex 1
KOG1, Mip1
Human RPTOR (57521), Mouse Rptor (74370), Rat Rptor (287871), domestic guinea pig Rptor (100729707), domestic cat RPTOR (101086862), naked mole-rat Rptor (101724257), cow RPTOR (507056), sheep RPTOR (101119321), Zebrafish rptor (560455), chicken RPTOR (428674)
- Human(57521) Summary: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(74370) regulatory associated protein of MTOR, complex 1
- Rat(287871) regulatory associated protein of MTOR, complex 1
- domestic guinea pig(100729707) regulatory associated protein of MTOR, complex 1
- domestic cat(101086862) regulatory associated protein of MTOR, complex 1
- naked mole-rat(101724257) regulatory associated protein of MTOR, complex 1
- cow(507056) regulatory associated protein of MTOR, complex 1
- sheep(101119321) regulatory associated protein of MTOR, complex 1
- Zebrafish(560455) regulatory associated protein of MTOR, complex 1
- chicken(428674) regulatory associated protein of MTOR, complex 1
- dog(608378) regulatory associated protein of MTOR, complex 1
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Antibodies
Anti-RPTOR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence
ANTI-PHOSPHO-RAPTOR(S863) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
human
Monoclonal Anti-RPTOR, (C-terminal) antibody produced in mouse, clone 3C2, purified immunoglobulin, buffered aqueous solution,
human
ELISA
Proteins
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
human