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TissueFab® bioink 

Alg(Gel)ma -Vis/525 nm

Synonim(y):

Alginate, Bioink, GelMA-Alginate bioink, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl, Sodium alginate

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1 EA
2000,00 zł

2000,00 zł

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1 EA
2000,00 zł

About This Item

Kod UNSPSC:
12352201
NACRES:
NA.23

2000,00 zł

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opis

suitable for 3D bioprinting applications

Postać

gel form (Viscous)

zanieczyszczenia

≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)

kolor

colorless to pale yellow

pH

6.5-7.5

Zastosowanie

3D bioprinting

temp. przechowywania

2-8°C

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Opis ogólny

3D bioprinting is the printing of biocompatible materials, cells, growth factors, and the other supporting materials necessary to yield functional complex living tissues. 3D bioprinting has been used to generate several different types of tissue such as skin, bone, vascular grafts, and cartilage structures. Based upon the desired properties, different materials and formulations can be used to generate both hard and soft tissues. While several 3D printing methods exist, due to the sensitivity of the materials used, extrusion-based methods with bioinks are most commonly employed.

Zastosowanie

Gelatin methacrylate-Alginate bioink formulation is derived from natural polymers - gelatin and alginate. Gelatin contains bioactive peptide sequences similar to native extracellular matrix which promotes integrin mediated cell adhesion and MMP sensitive enzymatic degradation which are essential for cellular functions such as migration, proliferation and differentiation. Alginate is a natural polysaccharide widely used in tissue engineering, serves as a viscosity enhancer in the bioink formulation. TissueFab®- GelAlg-Vis bioink formulation is optimized for 3D bioprinting of tissues and constructs using any extrusion based 3D bioprinter. TissueFab® - GelAlg-Vis bioink formulation can be used to bioprint cell-laden hydrogels in desired shape and can be crosslinked by a combination of chemical crosslinking and visible light mediated photocrosslinking for further culture and maturation of cells for tissue engineering and regenerative medicine applications. Gelatin methacrylate bioinks have been used for 3D bioprinting with high printing resolution, shape fidelity and cell viability[1][2]. Gelatin methacrylate based bioinks have been used to bioprint osteogenic[3], chondrogenic[2][4], hepatic[1][5][6], adipogenic[7], vasculogenic[8], epithelial[6], endothelial[9][10], cardiac valve[11], skin[12], tumor[10] and other tissues and constructs. Gelatin and alginate containing bioinks have been used for bioprinting of 3D constructs with various cell types including human mesenchymal stem cells (hMSC)[2][8], embryonic stem cells (ESC)[13], human umbilical vein endothelial cells (HUVEC)[8][10], fibroblasts[10], cancer cells[10] etc.

Opakowanie

10 mL in glass bottle

Informacje prawne

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
Ta strona może zawierać tekst przetłumaczony maszynowo.

Piktogramy

Health hazardExclamation mark
GHS08,GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H317,H373

Zwroty wskazujące środki ostrożności

P260 - P272 - P280 - P302 + P352 - P314 - P333 + P313

Klasyfikacja zagrożeń

Skin Sens. 1 - STOT RE 2

Organy docelowe

Liver,Upper respiratory tract

Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
MKCR3027
MKCM1874

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Liliang Ouyang et al.
Biofabrication, 8(3), 035020-035020 (2016-09-17)
3D cell printing is an emerging technology for fabricating complex cell-laden constructs with precise and pre-designed geometry, structure and composition to overcome the limitations of 2D cell culture and conventional tissue engineering scaffold technology. This technology enables spatial manipulation of
Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
Wanjun Liu et al.
Advanced healthcare materials, 6(12) (2017-05-04)
Bioprinting is an emerging technique for the fabrication of 3D cell-laden constructs. However, the progress for generating a 3D complex physiological microenvironment has been hampered by a lack of advanced cell-responsive bioinks that enable bioprinting with high structural fidelity, particularly
Weitao Jia et al.
Biomaterials, 106, 58-68 (2016-08-24)
Despite the significant technological advancement in tissue engineering, challenges still exist towards the development of complex and fully functional tissue constructs that mimic their natural counterparts. To address these challenges, bioprinting has emerged as an enabling technology to create highly
B Duan et al.
Acta biomaterialia, 10(5), 1836-1846 (2013-12-18)
Tissue engineering has great potential to provide a functional de novo living valve replacement, capable of integration with host tissue and growth. Among various valve conduit fabrication techniques, three-dimensional (3-D) bioprinting enables deposition of cells and hydrogels into 3-D constructs
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