Przejdź do zawartości
Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Synonimy:
LNCR2, NACHRA3, PAOD2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
(±)-Nicotine, ≥99% (TLC), liquid,
Gatunek
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
Gatunek
human, mouse, rat
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Gatunek
rat, human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Gatunek
human, mouse, rat
(−)-Nicotine, ≥99% (GC), liquid,
Gatunek
human, mouse, rat

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Cytisine, ≥99%, powder,
Gatunek
rat
(±)-Nicotine, ≥99% (TLC), liquid,
Gatunek
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
Gatunek
human, mouse, rat
Mecamylamine hydrochloride, ,
Gatunek
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Gatunek
rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, human, rabbit
Zastosowanie
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
chicken, eel, human
Zastosowanie
immunohistochemistry

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Hexamethonium chloride, solid (hygroscopic),
Gatunek
human
Tetraethylammonium chloride, ≥98% (titration),
Gatunek
human
Hexamethonium bromide, ,
Gatunek
human
Kynurenic acid, ≥98%,
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Chrna3,
Gatunek
mouse
MISSION® esiRNA, targeting human CHRNA3,
Gatunek
human