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BRD2

bromodomain containing 2

Synonimy:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(14312) bromodomain containing 2
  • Rat(294276) bromodomain containing 2
  • domestic guinea pig(100734555) bromodomain containing 2
  • cow(505358) bromodomain containing 2
  • Domestic Rabbit(100343906) bromodomain containing 2
  • domestic cat(101084362) bromodomain containing 2
  • sheep(101110276) bromodomain containing 2
  • chicken(417049) bromodomain containing 2
  • dog(474868) bromodomain containing 2
  • naked mole-rat(101699681) bromodomain containing 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-BRD2 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human, mouse, pig, rat
Zastosowanie
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Goat anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
OTX015, ≥98% (HPLC),
Gatunek
human
I-BET762, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
BRD2 (339-459) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
Gatunek
human
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
Gatunek
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Brd2,
Gatunek
mouse
MISSION® esiRNA, targeting human BRD2,
Gatunek
human