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品質等級
化驗
≥97% (TLC)
形狀
solid
效力
2 μM IC50
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
desiccated (hygroscopic)
顏色
off-white
溶解度
water: 50 mg/mL
運輸包裝
ambient
儲存溫度
−20°C
一般說明
一种精氨酸酶的有效、选择性、竞争性和高亲和力抑制剂。显示抑制大鼠肝脏（IC50 = 2 µM）和小鼠巨噬细胞（IC50 = 50 µM）的精氨酸酶。与酶活性位点的锰簇特异性相互作用。不充当NOS的底物或抑制剂。因此，它可能是研究精氨酸酶和NOS之间相互作用的有用工具。
一种精氨酸酶的有效、选择性、竞争性和高亲和力抑制剂。显示抑制大鼠肝脏（IC50 = 2 µM）和小鼠巨噬细胞（IC50 = 50 µM）的精氨酸酶。显示与酶活性位点的锰簇特异性相互作用。不作为NOS的底物或抑制剂起作用。因此，nor-NOHA可能是研究精氨酸酶和NOS之间相互作用的有用工具。
生化／生理作用
主要靶标
大鼠肝脏精氨酸酶
大鼠肝脏精氨酸酶
次要靶标
小鼠巨噬细胞（IC₅₀ = 50 µM）
小鼠巨噬细胞（IC₅₀ = 50 µM）
包裝
用惰性气体包装
警告
毒性：标准处理（A）
重構
复溶后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多6个月。
其他說明
Gobert, A.P., et al. 2000.Infect.Immun.68, 4653.
Meurs, H., et al. 2000.Br. J. Pharmacol.130, 1793.
Moali, C., et al. 2000.Biochemistry 39, 8208.
Tenu, J.P. et al. 1999.Nitric Oxide 3, 427.
Moali, C., et al. 1998.Biochemistry 37, 10453.
Custot, J., et al. 1997.J. Am. Chem. Soc.119, 4086.
Meurs, H., et al. 2000.Br. J. Pharmacol.130, 1793.
Moali, C., et al. 2000.Biochemistry 39, 8208.
Tenu, J.P. et al. 1999.Nitric Oxide 3, 427.
Moali, C., et al. 1998.Biochemistry 37, 10453.
Custot, J., et al. 1997.J. Am. Chem. Soc.119, 4086.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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