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About This Item
经验公式（希尔记法）:
C6H14N4O3 · C2H4O2
CAS号:
分子量:
250.25
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.77
推荐产品
化驗
≥98% (TLC)
形狀
powder
mp
204 °C
溶解度
acetic acid: 10 mg/mL, clear, colorless to faintly yellow
儲存溫度
2-8°C
SMILES 字串
CC(O)=O.N[C@@H](CCCNC(=N)NO)C(O)=O
InChI
1S/C6H14N4O3.C2H4O2/c7-4(5(11)12)2-1-3-9-6(8)10-13;1-2(3)4/h4,13H,1-3,7H2,(H,11,12)(H3,8,9,10);1H3,(H,3,4)/t4-;/m0./s1
InChI 密鑰
VYMCYRPQICLHKC-WCCKRBBISA-N
生化／生理作用
NG-羟基-L-精氨酸是精氨酸酶的生理抑制剂 。
通过NO合酶将精氨酸转化为NO和瓜氨酸过程中的中间体。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
The inhibition of arginase by N?-hydroxy-L-arginine controls the growth of Leishmania inside macrophages
Iniesta V, et al.
The Journal of Experimental Medicine, 193(6), 777-784 (2001)
T Pera et al.
The Journal of pharmacology and experimental therapeutics, 349(2), 229-238 (2014-02-25)
Airway inflammation and remodeling are major features of chronic obstructive pulmonary disease (COPD), whereas pulmonary hypertension is a common comorbidity associated with a poor disease prognosis. Recent studies in animal models have indicated that increased arginase activity contributes to features
Alexander Bollenbach et al.
Analytical biochemistry, 577, 59-66 (2019-04-28)
l-Homoarginine (hArg) is biosynthesized from l-arginine (Arg) and l-lysine (Lys) by arginine:glycine amidinotransferase (AGAT). AGAT also catalyzes the formation of guanidinoacetate (GAA) from Arg and glycine (Gly). GAA is converted to creatine (N-methyl guanidinoacetate) by guanidinoacetate N-methyl-transferase (GAMT). Low circulating
K L Campos et al.
The Journal of biological chemistry, 270(4), 1721-1728 (1995-01-27)
The nitric oxide synthase-catalyzed conversion of L-arginine to L-citrulline and nitric oxide is known to be the sum of two partial reactions: oxygenation of arginine to N-hydroxyarginine, followed by oxygenation of N-hydroxyarginine to citrulline and nitric oxide. Whereas the conversion
P Klatt et al.
The Journal of biological chemistry, 268(20), 14781-14787 (1993-07-15)
Brain NO (nitric oxide) synthase contains FAD, FMN, heme, and tetrahydrobiopterin as prosthetic groups and represents a multi-functional oxidoreductase catalyzing oxidation of L-arginine to NO and L-citrulline, formation of H2O2, and reduction of cytochrome c. We show that substrate analogues
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