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Merck

452483

Sigma-Aldrich

1-甲基---色氨酸

95%, for peptide synthesis

别名:

(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan

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About This Item

经验公式(希尔记法):
C12H14N2O2
分子量:
218.25
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

产品名称

1-甲基---色氨酸, 95%

品質等級

化驗

95%

形狀

lumps and powder

光學活性

[α]22/D +12.4°, c = 2 in acetic acid

反應適用性

reaction type: solution phase peptide synthesis

mp

242-245 °C (lit.)

應用

peptide synthesis

SMILES 字串

Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1

InChI 密鑰

ZADWXFSZEAPBJS-SNVBAGLBSA-N

應用

用于通过色氨酸酯与醛的 Pictet-Spengler 反应,制备多种天然产物,包括大灵碱生物碱,也可用于合成 1-取代 indolactam 前体。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Zhidan Tu et al.
Stem cells and development, 19(11), 1803-1809 (2010-02-19)
Mesenchymal stem cells (MSCs) possess potent and broad immunosuppressive capabilities, and have shown promise in clinical trials treating many inflammatory diseases. Previous studies have found that MSCs inhibit dendritic cell, T-cell, and B-cell activities in the adaptive immunity; however, whether
Franco Carranza et al.
PloS one, 7(7), e40356-e40356 (2012-08-01)
Dendritic cells (DC) have the potential to control the outcome of autoimmunity by modulating the immune response. In this study, we tested the ability of Fasciola hepatica total extract (TE) to induce tolerogenic properties in CpG-ODN (CpG) maturated DC, to
Irie, K. et al.
Tetrahedron, 51, 6255-6255 (1995)
Cook, J.M. et al.
Heterocycles, 27, 2795-2795 (1988)
Michael J Quaney et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(3), e2205049120-e2205049120 (2023-01-13)
Stimulator of interferon genes (STING) signaling has been extensively studied in inflammatory diseases and cancer, while its role in T cell responses to infection is unclear. Using Listeria monocytogenes strains engineered to induce different levels of c-di-AMP, we found that

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