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Merck

191892

Sigma-Aldrich

Hydroxypropylcellulose

average Mw ~370,000, powder, 20 mesh particle size (99% through)

Synonym(e):

HPC

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
NACRES:
NA.23

Beschreibung

biological oxygen demand (BOD) 14,000 ppm

Qualitätsniveau

Form

powder

Selbstzündungstemp.

752 °F

Mol-Gew.

average Mw ~370,000

Verunreinigungen

<5 wt. %

Partikelgröße

20 mesh (99% through)

pH-Wert

5.0-8.5

Grenzflächenspannung Mineralöl

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

Viskosität

150-400 cP, 2 wt. % in H2O(25 °C, Brookfield, spindle #2) (60 rpm)(lit.)

Löslichkeit

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

Dichte

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChIKey

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Hydroxypropyl cellulose (HPC) is a nonionic derivativeof cellulose. It is a thermosensitive, biodegradable polymer with low criticalsolution temperature.

Anwendung

Hydroxypropyl cellulose can be used to prepare composite nanospheres for drug delivery systems. Hydroxypropyl methacrylate/hydroxy cellulose graft copolymers can be used as matrices for controlled-release tablets. It can also be used as an electrolyte additive to prepare gel polymerelectrolytes for dye-sensitized solar cells.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Catherine Boissier et al.
Journal of pharmaceutical sciences, 101(7), 2512-2522 (2012-04-28)
Nuclear magnetic resonance (NMR) cryoporometry and scanning electron microscopy (SEM) image analysis have been used to investigate the size and shape distribution of pores in pharmaceutical coatings. The coatings were made from a mixture of hydroxypropylcellulose (HPC) and ethylcellulose (EC).
A Aykut-Yetkiner et al.
Journal of dental research, 92(3), 289-294 (2013-01-15)
The objective of this in vitro study was to investigate the effects of viscosity changes of different acidic solutions on dental erosion. Bovine enamel samples (n = 240, Ø = 3 mm) were embedded in acrylic resin and were allocated
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
Chirangano Mangwandi et al.
International journal of pharmaceutics, 427(2), 328-336 (2012-03-07)
Being able to predict the properties of granules from the knowledge of the process and formulation variables is what most industries are striving for. This research uses experimental design to investigate the effect of process variables and formulation variables on
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of

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