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Merck

191906

Sigma-Aldrich

Hydroxypropylcellulose

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
NACRES:
NA.23

Beschreibung

biological oxygen demand (BOD) 14,000 ppm

Qualitätsniveau

Form

powder

Selbstzündungstemp.

752 °F

Mol-Gew.

average Mw ~1,000,000

Verunreinigungen

<5 wt. %

Partikelgröße

20 mesh (99% through)

pH-Wert

5.0-8.5

Grenzflächenspannung Mineralöl

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

Viskosität

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

Löslichkeit

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

Dichte

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChIKey

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Anwendung

  • Thermo-responsive aqueous foams: Hydroxypropyl cellulose has been studied for its properties as a green polymer that can alter its solubility with temperature changes, making it suitable for responsive foam applications (Braunschweig, 2019).
  • Interaction mechanism in aqueous solutions: A study on the interaction between hydroxypropyl cellulose and water in solutions, focusing on the importance of polymer chain length in determining the physical properties of the solutions (Martin-Pastor and Stoyanov, 2020).
  • Corrosion inhibition: Hydroxypropyl cellulose has shown effectiveness as a corrosion inhibitor for aluminium in acidic environments, highlighting its potential in material science and engineering applications (Nwanonenyi et al., 2019).
  • Orally disintegrating films: This application involves the formulation design of hydroxypropyl cellulose films, aiming to enhance the delivery and dissolution profile of pharmaceuticals, making it significant in drug delivery and pharmaceutical sciences (Takeuchi et al., 2018).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Catherine Boissier et al.
Journal of pharmaceutical sciences, 101(7), 2512-2522 (2012-04-28)
Nuclear magnetic resonance (NMR) cryoporometry and scanning electron microscopy (SEM) image analysis have been used to investigate the size and shape distribution of pores in pharmaceutical coatings. The coatings were made from a mixture of hydroxypropylcellulose (HPC) and ethylcellulose (EC).
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
Maya Fujiwara et al.
Chemical & pharmaceutical bulletin, 60(11), 1380-1386 (2012-11-06)
We evaluated models for predicting spray mist diameter suitable for scaling-up the fluidized bed granulation process. By precise selection of experimental conditions, we were able to identify a suitable prediction model that considers changes in binder solution, nozzle dimension, and
Hyemin Choi et al.
Journal of pharmaceutical sciences, 101(8), 2941-2951 (2012-05-26)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystallization technique has been widely applied to inorganic materials, although it has seldom been used with drugs. In this study
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of

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