1460703

ネビラピン

United States Pharmacopeia (USP) Reference Standard

• 別名: Nevirapine, 11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
• 実験式（ヒル表記法）: C₁₅H₁₄N₄O
• CAS番号: 129618-40-2
• 分子量: 266.30
• MDL番号: MFCD00866928
• UNSPSCコード: 41116107
• PubChem Substance ID: 329750549
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: nevirapine
• メーカー／製品名: USP
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• SMILES記法: CC1=CC=NC2=C1NC(C(C=CC=N3)=C3N2C4CC4)=O
• InChI: 1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
• InChI Key: NQDJXKOVJZTUJA-UHFFFAOYSA-N

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Nevirapine anhydrous USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Nevirapine
• Nevirapine Extended-Release Tablets
• Nevirapine Oral Suspension
• Nevirapine Tablets

生物化学的／生理学的作用

HIV-1のNNRTI(非ヌクレオシド系逆転写酵素阻害剤)です。

ネビラピンは、アロステリックで非ヌクレオシド系のHIV逆転写酵素阻害剤(NNRTI)です。ネビラピンによる野生型逆転写の阻害のK_iの値は200 nMです。

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

Sales restrictions may apply.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable