1143008

コカイン 塩酸塩

United States Pharmacopeia (USP) Reference Standard

• 別名: エクゴニンメチルエステルベンゾアート 塩酸塩
• 実験式（ヒル表記法）: C₁₇H₂₁NO₄ · HCl
• CAS番号: 53-21-4
• 分子量: 339.81
• MDL番号: MFCD00058119
• UNSPSCコード: 41116107
• PubChem Substance ID: 329749446
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: cocaine
• メーカー／製品名: USP
• 薬剤管理: USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• SMILES記法: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1
• InChI Key: PIQVDUKEQYOJNR-VZXSFKIWSA-N

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Cocaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cocaine
• Cocaine Hydrochloride
• Cocaine Hydrochloride Tablets for Topical Solution

生物化学的／生理学的作用

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

Sales restrictions may apply.

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H300 + H330,H336,H361d
• 注意書き: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310
• 危険有害性の分類: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable