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Merck
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主要文書

安全性情報

SRE0055

Sigma-Aldrich

プロテアーゼインヒビターカクテル粉末

Reagents designed and manufactured under cGMP controls suitable for use in an IVD application.

別名:

Protease Inhibitor Cocktail powder

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About This Item

UNSPSCコード:
12352200
NACRES:
NA.32

由来生物

bovine lung
yeast

フォーム

lyophilized powder

保管温度

−20°C

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特異性

Inhibits serine, cysteine, and metallo-proteases.

アプリケーション

Optimized and tested for general use.
Protease inhibitor cocktail powder has been used in immunoblotting and immunoprecipitation.

生物化学的/生理学的作用

This mixture contains individual components, including AEBSF at 2 mM, Aprotinin at 0.3 μM, Bestatin at 116 μM, E-64 at 14 μM, Leupeptin at 1 μM and EDTA at 1 mM. Each component has specific inhibitory properties.

AEBSF and Aprotinin act to inhibit serine proteases, including trypsin, chymotrypsin, and plasmin amongst others. Bestatin inhibits aminpeptidases. E-64 acts against cystein proteases. EDTA is an inhibitor of metalloproteases. Leupeptin acts against both serine and cystein proteases.
Protease helps to break down proteins into soluble peptides and amino acids.

構成

1 bottle in serum bottle
Components
AEBSF
Aprotinin
Bestatin
E-64
EDTA
Leupeptin

数量

One bottle makes 100 mL of cocktail, which are sufficient to the inhibition of proteases present in approximately 20 gram of cell extract.
Not all extracts contain the same levels of endogenous enzymes, and it may be necessary to adjust the volume of cocktail required.

調製ノート

This product is supplied as a lyophilized powder. One bottle prepares 100 mL of a cocktail solution.

ピクトグラム

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シグナルワード

Warning

危険有害性情報

危険有害性の分類

Eye Irrit. 2 - Skin Irrit. 2

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

SRE0055-1BTL:
SRE0055-1BO:
SRE0055-VAR:
SRE0055-1BO-PW:
SRE0055-BULK:


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Biology for the IB Diploma: Standard and Higher Level (2001)
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Molecular and cellular biochemistry (2024-06-28)
Bisphenol A (BPA), a common endocrine-disrupting chemical, is found in a wide range of home plastics. Early-life BPA exposure has been linked to neurodevelopmental disorders; however, the link between neuroinflammation, pyroptosis, and the development of psychiatric disorders is rarely studied.

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