SML0818

A-841720

≥98% (HPLC)

• 別名: 9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one
• 実験式（ヒル表記法）: C₁₇H₂₁N₅OS
• CAS番号: 869802-58-4
• 分子量: 343.45
• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 15 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [s]1c2nccc(c2c3nc[n]([c](c31)=O)N4CCCCCC4)N(C)C
• InChI: 1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
• InChI Key: GYWGXEGOXODOQU-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.

A-841720 is a potent, selective, non-competitive mGluR1 antagonist.

特徴および利点

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable