SML0807

PreQ1 dihydrochloride

≥98% (HPLC)

• 別名: 2-Amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride, 7-Aminomethyl-7-deazaguanine dihydrochloride, Pre-queuosine1 dihydrochloride
• 実験式（ヒル表記法）: C₇H₉N₅O · 2HCl
• CAS番号: 86694-45-3
• 分子量: 252.10
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to light brown
• 溶解性: DMSO: 5 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: Cl.Cl.[nH]1c2nc([nH][c](c2c(c1)CN)=O)N
• InChI Key: WUMBRQKOLVTYTB-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

PreQ1 (pre-queuosine1) is an intermediate of the queuosine pathway. Also, PreQ1 binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.

PreQ1 (pre-queuosine1), an intermediate of the queuosine pathway, regulates the PreQ1 riboswitch.

PreQ1 is a nucleobase derived from guanine[1] and a precursor of the modified base queuosine that is present in four tRNAs.[2] Prequeuosine (preQ1) riboswitches are RNA regulatory elements present in the 5′ UTR of genes that participates in the biosynthesis and transport of preQ1.[2]

特徴および利点

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安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable