SML0588

CP-94,253 dihydrochloride

≥98% (HPLC)

• 別名: 1,4-ジヒドロ-3-(1,2,3,6-テトラヒドロ-4-ピリジニル)-5H-ピロール[3,2-b]ピリジン-5-オン 二塩酸塩
• 実験式（ヒル表記法）: C₁₅H₁₉N₃O · 2HCl
• CAS番号: 131084-35-0
• 分子量: 330.25
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825567
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: H₂O: 15 mg/mL, clear
• 保管温度: room temp
• SMILES記法: Cl.Cl.CCCOc1ccc2[nH]cc(C3=CCNCC3)c2n1
• InChI: 1S/C15H19N3O.2ClH/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11;;/h3-5,10,16-17H,2,6-9H2,1H3;2*1H
• InChI Key: HGFPLQPNCZQRLO-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.

CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable