ELISA: suitable dot blot: suitable immunoblotting: 1-2 μg/mL using recombinant human collagen, expressed in Nicotiana tabacum immunohistochemistry: 3.5-7 μg/mL using frozen sections of human tonsil, human tongue or pig tongue
Collagen type Iα1 (COL1A1) is encoded by the gene that is located on human chromosome 17q21.33. It is the most abundant extracellular matrix (ECM) protein in humans. Type 1 collagen is the major structural protein of bone, tendon, skin and cornea. The encoded protein is a heterotrimer consisting of two α1-chains and one α2-chain.
Collagens are present in the extracellular matrix and contains a chains which can differ in length.
免疫原
bovine skin collagen type I
アプリケーション
Monoclonal Anti-Collagen Type I antibody produced in mouse has been used in immunohistochemical analysis and in vitro invasion assays.
生物化学的／生理学的作用
Collagen, type I (COL1A1) is an important component of the connective tissue matrix. It plays an important role in the growth and maintenance of organ and tissue integrity. This protein also participates in the process of tissue repair. COL1A1 is implicated in fibrosis.
Collagens are involved in structural roles. Additionally, they associate with various receptors and control cell proliferation, migration as well as differentiation.
物理的形状
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
International journal of molecular sciences, 25(14) (2024-07-27)
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Paeoniflorin prevents postoperative peritoneal adhesion formation in an experimental rat model.
Gao Q, et al.
Oncotarget, 8(55), 93899-93899 (2017)
Fibrosis-related gene expression in the prostate is modulated by doxazosin treatment.
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