The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(15), 6179-6194 (2015-04-17)
Botulinum neurotoxin type A (BoNT/A) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic cleavage of the exocytic machinery component SNAP25 in motor nerve terminals. However, recent evidence suggests that the neurotoxic activity of BoNT/A is not restricted
Down-regulation of alphav/beta3 integrin via misrouting to lysosomes by overexpression of a beta3Lamp1 fusion protein
Conesa M, et al.
The Biochemical Journal, 370(2), 703-711 (2003)
Saponins modulate the intracellular trafficking of protein toxins.
Weng A
Journal of Controlled Release : Official Journal of the Controlled Release Society, 164, 74-86 (2012)
Journal of virology, 89(20), 10442-10452 (2015-08-08)
The human papillomavirus (HPV) capsid is composed of the major capsid protein L1 and the minor capsid protein L2. During entry, the HPV capsid undergoes numerous conformational changes that result in endosomal uptake and subsequent trafficking of the L2 protein
Journal of proteomics, 75(5), 1547-1562 (2011-12-08)
Dendritic cells (DC) take up pathogens through phagocytosis and process them into protein and lipid fragments for presentation to T cells. So far, the proteome of the human DC phagosome, a detrimental compartment for antigen processing and presentation as well
