C1240

Chlormethiazole hydrochloride

≥98% (HPLC), powder

• 別名: 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
• 実験式（ヒル表記法）: C₆H₈ClNS · HCl
• CAS番号: 6001-74-7
• 分子量: 198.11
• MDL番号: MFCD00673948
• UNSPSCコード: 12352200
• PubChem Substance ID: 329774745
• NACRES: NA.77

特性

• 詳細: Store desiccated
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: off-white
• 溶解性: H₂O: soluble >10 mg/mL
• オーガナイザー: AstraZeneca
• SMILES記法: Cl.Cc1ncsc1CCCl
• InChI: 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
• InChI Key: OFXYKSLKNMTBHK-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus.[1] Long term administration of chlormethiazole leads to addiction to the drug.[2]

GABA_A agonist; glycine receptor modulator.

特徴および利点

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H317,H318
• 注意書き: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves