73677

4-ニトロフェニル β-D-グルクロニド

β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test

• 別名: 4-ニトロフェニル-β-D-グルコピラノシドウロン酸, PNPG
• 実験式（ヒル表記法）: C₁₂H₁₃NO₉
• CAS番号: 10344-94-2
• 分子量: 315.23
• Beilstein: 1438576
• EC Number: 233-753-0
• MDL番号: MFCD00036210
• UNSPSCコード: 12352204
• PubChem Substance ID: 57652486
• NACRES: NA.32

特性

• 製品名: 4-ニトロフェニル β-D-グルクロニド, ≥99.0% (TLC)
• アッセイ: ≥99.0% (TLC)
• フォーム: powder or crystals
• 光学活性: [α]20/D −102±3°, c = 1% in ethanol
• 不純物: ≤0.05% free 4-nitrophenol; ≤7% water
• 溶解性: H₂O: 0.1 g/mL, clear, faintly yellow
• 適合性: suitable as substrate for β-glucuronidase test
• 保管温度: −20°C
• SMILES記法: O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O
• InChI: 1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
• InChI Key: QSUILVWOWLUOEU-GOVZDWNOSA-N

詳細

アプリケーション

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples,[1] β-glucuronidase activity of bacteria in caecum content digesta[2] and bovine liver.[3] It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.[4]

基質

β-グルクロニダ-ゼ(GUS)遺伝子検出用呈色基質。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)