37019

アトロピン

analytical standard

• 別名: endo-(±)-α-(ヒドロキシメチル)ベンゼン酢酸 8-メチル-8-アザビシクロ[3.2.1]オクト-3-イルエステル, トロピントロパ酸エステル, ヒヨスシアミン
• 実験式（ヒル表記法）: C₁₇H₂₃NO₃
• CAS番号: 51-55-8
• 分子量: 289.37
• Beilstein: 91260
• EC Number: 200-104-8
• MDL番号: MFCD00022622
• UNSPSCコード: 85151701
• PubChem Substance ID: 329755584
• NACRES: NA.24

特性

• グレード: analytical standard
• シェルフライフ: limited shelf life, expiry date on the label
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: cleaning products; cosmetics; food and beverages; personal care
• フォーマット: neat
• 保管温度: −20°C
• SMILES記法: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?
• InChI Key: RKUNBYITZUJHSG-SPUOUPEWSA-N
• 遺伝子情報: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

詳細

詳細

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.[1]

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.[1]
For the analysis of the phytotoxins.

アプリケーション

Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).[2]
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.[3]
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.[4]
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.[5]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:

• Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).[2]
• Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.[3]
• Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.[4]
• Plant materials by liquid-liquid extraction and EXtrelut^® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.[5]

生物化学的／生理学的作用

中枢および末梢のアセチルコリンレセプタ-に対する非選択的な競合性アンタゴニストです。

再構成

Dried down, ~100μg/mL after reconstitution with 1 mL of water

アナリシスノート

purity : ≥96.0% (HPLC)

法的情報

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H300 + H330
• 注意書き: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• 危険有害性の分類: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable