GF423

IL-2, Human

HumanKine^®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

特性

• product name: HumanKine^® IL-2, Human Recombinant Xeno-Free,
• アッセイ: >95% (SDS-PAGE)
• 品質水準: 300
• 特徴: endotoxin free
• UniProtアクセッション番号: P60568

詳細

詳細

HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.

Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be interesting clinical targets for those diseases. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies.

品質

Bioactivity assay: Determined by the dose-dependent stimulation of the proliferation of mouse CTLL-2 cells (mouse cytotoxic T cell
line). ED50 is typically 0.2-2 ng/ml.

HumanKine IL-2 is manufactured using all non-animal reagents and is considered Xeno-Free

物理的形状

Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization.

保管および安定性

Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.

法的情報

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.