CD15 is a carbohydrate antigen carried by both glycoproteins and glycoliplds. The structure of the antigen was determined to be Galb1→4[Fuca1→3]GIcNACb1→3Galb1→R. CD15 serves as a ligand for selectins and might also be involved in cell adhesion through a direct Lewis X-Lewis X interaction. CD15 is expressed mainly on mature granulocytes and monocytes but also on immature bone marrow cells (Kannagi, 1997). Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).
特異性
Antibody recognizes Human CD15 antigen.
免疫原
Purified human neutrophils
アプリケーション
This Milli-Mark Anti-CD15-FITC Antibody, clone C3D-1 is validated for use in FC for the detection of CD15.
品質
Evaluated by flow cytometry using human PBMCs
物理的形状
Activated Sepharose
Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法的情報
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
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