252805

DHEA

≥97% (HPLC), powder, GABAA receptor negative modulator, Calbiochem^®

• 別名: DHEA, Dehydro- epi-androsterone, Dehydroisoandrosterone, Prasterone, 3-Hydroxyandrost-5-en-17-one
• 実験式（ヒル表記法）: C₁₉H₂₈O₂
• CAS番号: 53-43-0
• 分子量: 288.42
• MDL番号: MFCD00003613
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• 製品名: DHEA, Major secretory steroidal product of the adrenal gland.
• 品質水準: 100
• 詳細: Merck USA index - 14, 2871
• アッセイ: ≥97% (HPLC)
• フォーム: powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: off-white
• 溶解性: ethanol: 20 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• SMILES記法: O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@](CC3)(C(=O)CC4)C)CC=C2C1)C
• InChI: 1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15-,16-,18-,19-/m0/s1
• InChI Key: FMGSKLZLMKYGDP-USOAJAOKSA-N

詳細

詳細

Major secretory steroidal product of the adrenal gland. DHEA and its sulfated metabolite, DHEA-S, are negative modulators of GABA_A receptors.

Major secretory steroidal product of the adrenal gland. DHEA, and its sulfated metobolite DHEA-S, are negative modulators of GABA_A receptors.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Negative modulators of GABAA receptors

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

その他情報

Hansen, S.L., et al. 1999. Mol. Pharmacol. 55, 489.
Imamura, M., and Prasad, C. 1998. Biochem. Biophys. Res. Commun.243, 771.
Majewska, M.D., et al. 1990. Brain Res.526, 143.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Warning
• 危険有害性情報: H361fd
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable