Complement C3a, Human, Complement C3a, Human, is a native, single chain C3a complement component. It has many biological activities, such as smooth muscle contraction, platelet activation, & immunoregulatory reactions.
Native, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzyme (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77, resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities, which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
物理的形状
In PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
調製ノート
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
再構成
Following initial thaw, aliquot and freeze (-70°C).