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アッセイ
>99% (TLC)
フォーム
powder
包装
pkg of 1 × 50 μg (810215P-50ug)
メーカー／製品名
Avanti Research™ - A Croda Brand 810215P
輸送温度
dry ice
保管温度
−20°C
SMILES記法
N[C@H]([C@H](O)[C@H](O)CCCCCCCCCCCCCC)CO
InChI
1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChI Key
AERBNCYCJBRYDG-KSZLIROESA-N
関連するカテゴリー
詳細
C12-NBD Phytosphingosine is a fluorescent derivative of the naturally occurring lipid compound, phytosphingosine which is localised in skin, kidney and intestines.[1][2]
Phytosphingosine is a ceramide molecule localized to the stratum corneum.[3]
アプリケーション
C12-NBD Phytosphingosine has been used as a substrate in ceramidase activity assay to study enzyme activity.[4]
C12-NBD phytosphingosine has been used as a substrate to assay ceramidase activity.[4]
生物化学的／生理学的作用
In vitro studies using human epidermis model shows that melanin production is prevented by phytosphingosine. Hence, it is widely used in cosmetics.[5]
Phytosphingosine (PHS) is a sphingoid lipid molecule which is known to exhibit antimicrobial and anti-inflammatory action. PHS can has the ability to increase the production of keratinocyte differentiation marker proteins, such as transglutaminase 1 and involucrin, that are responsible for the development of cornifed envelope.[2] PHS metabolism results in the formation of glycerophospholipids, sphingolipids and even-numbered fatty acids which mainly include palmitic acid.[6]
包装
5 mL Amber Glass Screw Cap Vial (810215P-50ug)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
810215P-50UG:
810215P-VAR:
810215P-BULK:
最新バージョンのいずれかを選択してください：
Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway
Jang EL, et al.
Journal of Dermatological Science, 87(1), 19-28 (2017)
Fluorescent and Luminescent Probes for Biological Activity (1999)
Phytosphingosine and sphingosine ceramide headgroup hydrogen bonding: structural insights through thermotropic hydrogen/deuterium exchange
Rerek ME, et al.
The Journal of Physical Chemistry B, 105(38), 9355-9362 (2001)
Hyun Kyung Choi et al.
Archives of dermatological research, 309(10), 795-803 (2017-09-25)
Phytosphingosine (PHS) is a sphingoid that is a key component of phytoceramides NP, AP and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differentiation. In addition, it is reported that PHS treatment notably
Li-Yu Chen et al.
Nature communications, 6, 6030-6030 (2015-01-17)
Turgor pressure plays pivotal roles in the growth and movement of walled cells that make up plants and fungi. However, the molecular mechanisms regulating turgor pressure and the coordination between turgor pressure and cell wall remodelling for cell growth remain
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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