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liquid
メーカー／製品名
Avanti Research™ - A Croda Brand
包装
1 ea of 1 × (ELISA strip packaged in foil pouch)
輸送温度
wet ice
保管温度
2-8°C
詳細
Avanti Lipid Snoopers™ are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods.[1] Sphingomyelin (SM) is a sphingolipid present in central nervous system as a component of the myelin sheath and neuronal cells.[2] It is synthesized from ceramide in Golgi.[3] Acid sphingomyelinase (aSMase) degrades SM.[3]
ELISA Snoopers™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
- quantitative lipid-protein binding studies
- assemble a 96-well plate using only the lipids of interest for binding studies
- flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
生物化学的／生理学的作用
Sphingomyelin (SM) participates in the inflammatory process and signalling pathways. It is a crucial regulator for myelin integrity, axon maturation, cognition and brain development.[2] The SM to ceramide ratio is crucial, as high ceremide levels are implicated in depression.[3] Altered levels of sphingomyelin due to sphingomyelinase deficiency results in Niemann–Pick disease.[4]
包装
ELISA Strip Packaged in Foil Pouch (330678-1EA)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC
保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
No data available
引火点(℃)
No data available
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
330678-VAR:
330678-1EA:
最新バージョンのいずれかを選択してください：
Sphingomyelin in brain and cognitive development: preliminary data
Schneider N, et al.
eNeuro (2019)
Sphingolipids: membrane microdomains in brain development, function and neurological diseases
Olsen ASB and Faergeman NJ
Open Biology, 7(5), 170069-170069 (2017)
Sphingolipid metabolism in neural cells
van ED, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1758(12), 1978-1994 (2006)
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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