ALD00034

(S)-tert-Butyl 1-(chloromethyl)-5-hydroxy-1H-benzo[e]indole-3(2H)-carboxylate

95% (HPLC)

• 別名: N-Boc-seco-CBI
• 実験式（ヒル表記法）: C₁₈H₂₀ClNO₃
• CAS番号: 130007-86-2
• 分子量: 333.81
• MDL番号: MFCD29059844
• UNSPSCコード: 12352200
• PubChem Substance ID: 329772532
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 95% (HPLC)
• フォーム: powder
• 光学活性: [α]/D -89.0, c = 0.05% in chloroform
• 保管温度: −20°C
• SMILES記法: OC1=C2C(C=CC=C2)=C3C(N(C(OC(C)(C)C)=O)C[C@H]3CCl)=C1
• InChI: 1S/C18H20ClNO3/c1-18(2,3)23-17(22)20-10-11(9-19)16-13-7-5-4-6-12(13)15(21)8-14(16)20/h4-8,11,21H,9-10H2,1-3H3/t11-/m1/s1
• InChI Key: DGPQGWRHSMFTSW-LLVKDONJSA-N

詳細

アプリケーション

N-Boc-CBI best used as its seco precursor (seco-N-Boc-CBI) is a simple alkylation subunit analog of that found in the naturally occurring antitumor agents the duocarmycins, yatakemycin, and CC-1065, which act by sequence selective DNA alkylation.

その他情報

Design, Synthesis, and Evaluation of Duocarmycin O-Amino Phenol Prodrugs Subject to Tunable Reductive Activation

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H410
• 注意書き: P273 - P501
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable