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Merck

GRIA1

glutamate receptor, ionotropic, AMPA 1

別名:
GLUH1, GLUR1, GLURA, GluA1, HBGR1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2890) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14799) glutamate receptor, ionotropic, AMPA1 (alpha 1)
  • Rat(50592) glutamate receptor, ionotropic, AMPA 1
  • dog(489168) glutamate receptor, ionotropic, AMPA 1
  • domestic cat(101097621) glutamate receptor, ionotropic, AMPA 1
  • naked mole-rat(101724828) glutamate receptor, ionotropic, AMPA 1
  • domestic guinea pig(100727046) glutamate receptor, ionotropic, AMPA 1
  • sheep(443271) glutamate receptor, ionotropic, AMPA 1
  • Domestic Rabbit(100348217) glutamate receptor, ionotropic, AMPA 1
  • chicken(414893) glutamate receptor, ionotropic, AMPA 1
  • Horse(100060020) glutamate receptor, ionotropic, AMPA 1
  • cow(529618) glutamate receptor, ionotropic, AMPA 1

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Small Molecule - Agonist

製品番号
詳細
Species
ATPA, solid,
Species
human, rat
2,6-ジフルオロ-4-[2-(フェニルスルホニル­アミノ)­エチルチオ]フェノキシアセトアミド, ≥98% (HPLC), solid,
Species
human
キスカル酸, powder,
Species
rat
シクロチアジド, ,
Species
human, rat
N-メチル-D-アスパラギン酸, ≥98% (TLC), solid,
Species
human, rat

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
CX546, ≥98% (HPLC), solid,
Species
human
ピラセタム, ,
Species
human, rat
シクロチアジド, ,
Species
human, rat
ジアゾキシド, ,
Species
rat, mouse, human
カイニン酸 一水和物, ≥99% (TLC),
Species
human, mouse, rat

Small Molecule - Antagonist

製品番号
詳細
Species
2,3-ピリジンジカルボン酸, 99%,
Species
rat
2,3-ジヒドロキシキノキサリン, 98%,
Species
rat
GYKI 52466 塩酸塩, solid,
Species
human
ATPA, solid,
Species
human, rat
ピラセタム, ,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
抗グルタミン酸受容体1抗体, from rabbit, purified by affinity chromatography,
交差性
equine, horse, human, mouse, platypus, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-GluR1 Antibody, clone C3T, rabbit monoclonal, culture supernatant, clone C3T, Upstate®,
交差性
chimpanzee, human, mouse, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
抗pan-AMPA受容体(GluR1-4)、クローン2D8抗体, clone 2D8, from mouse,
交差性
human, rat
アプリケーション
ELISA
electron microscopy

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
抗GluR1-NT(NT)抗体、クローンRH95, clone RH95, from mouse,
交差性
rat
アプリケーション
ELISA
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-phospho-GluR1 (Ser831) Antibody, clone N453, rabbit monoclonal, culture supernatant, clone N453, Upstate®,
交差性
chicken, human, mouse, rat
アプリケーション
western blot

Small Molecule - Blocker

製品番号
詳細
Species
シクロチアジド, ,
Species
human, rat
キヌレン酸, ≥98%,
Species
rat, human
トピラマート, United States Pharmacopeia (USP) Reference Standard,
Species
human
トピラマート, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
トピラマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Ligand

製品番号
詳細
Species
キスカル酸, powder,
Species
rat
2-ブロモ-2-クロロ-1,1,1-トリフルオロエタン, ≥99%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
ATPA, solid,
Species
human, rat
シクロチアジド, ,
Species
human, rat
(±)-AMPA, solid,
Species
rat
カイニン酸 一水和物, ≥99% (TLC),
Species
human, mouse, rat
L-グルタミン酸, ReagentPlus®, ≥99% (HPLC),
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GRIA1,
Species
human