コンテンツへスキップ
Merck

ADRA2A

adrenoceptor alpha 2A

別名:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Species:
UniProtKB ID:
遺伝子ID:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

製品番号
詳細
Species
クロニジン 塩酸塩, solid,
Species
human
キシラジン 塩酸塩, ≥99.0% (HPLC),
Species
human
(−)-3-(3,4-ジヒドロキシフェニル)-2-メチル-L-アラニン セスキ水和物, 99%,
Species
human
グアナベンズ 酢酸塩, powder,
Species
human
グアンファシン 塩酸塩, ≥98% (HPLC),
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
1-ナフチルメチルアミン, 97%,
Species
rat
ヨヒンビン 塩酸塩, ≥98% (HPLC), powder,
Species
human
1,2,3,4-テトラヒドロイソキノリン, 95%,
Species
rat, human
イダゾキサン 塩酸塩, ,
Species
human
RX 821002 塩酸塩, solid, ≥98% (HPLC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
抗ADRA2A抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
immunocytochemistry

immunofluorescence
抗ADRA2A抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, pig, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Blocker

製品番号
詳細
Species
ミアンセリン 塩酸塩, ,
Species
human
アグマチン 硫酸塩, ≥97%, powder,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
UK 14,304, ,
Species
human
BP897, >98% (HPLC), solid,
Species
human, rat
(−)-ノルエピネフリン, ≥98%, crystalline,
Species
human, rat
ハロペリドール, powder,
Species
human, rat
クロザピン, ,
Species
human, rat

Proteins

製品番号
詳細
Species
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human