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47865-U

Supelco

Nicotinamide (Niacinamide)

analytical standard

Sinonimo/i:

Nicotinamide, NAM, NIC, Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

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1000 MG
47,30 €

47,30 €

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Cambia visualizzazione
1000 MG
47,30 €

About This Item

Formula empirica (notazione di Hill):
C6H6N2O
Numero CAS:
98-92-0
Peso molecolare:
122.12
Beilstein:
383619
Numero CE:
202-713-4
Numero MDL:
MFCD00006395
Codice UNSPSC:
85151701
ID PubChem:
329757343
NACRES:
NA.24

47,30 €

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Richiedi un ordine bulk

Grado

analytical standard

Livello qualitativo

100

CdA

current certificate can be downloaded

Caratteristiche

standard type water soluble vitamin

Confezionamento

ampule of 1000 mg

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

128-131 °C (lit.)

applicazioni

clinical testing

Formato

neat

Temperatura di conservazione

2-30°C

Stringa SMILE

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
DFPAKSUCGFBDDF-UHFFFAOYSA-N

Informazioni sul gene

human ... PARP1(142) , SIRT2(22933)

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Categorie correlate

Descrizione generale

Nicotinamide (Niacinamide), belonging to the class of water-soluble B vitamins, is typically produced from nicotinic acid (vitamin B3). It is found as a component of food products. It has been suggested for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It also exhibits anti-inflammatory activity.[1][2]

Applicazioni

Nicotinamide (Niacinamide) may be used as a reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.[1][3][4][5]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H319

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

302.0 °F - closed cup

Punto d’infiammabilità (°C)

150 °C - closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
LRAD0860
LC25290V
LC24723V
LC23843V
LC22915V

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Niacinamide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1033

Niacinamide

Niacinamide meets USP testing specifications

Sigma-Aldrich

N5535

Niacinamide

Nicotinamide (Vitamin B3) solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

V-016

Nicotinamide (Vitamin B3) solution

Nicotinamide 1,N6-ethenoadenine dinucleotide ≥98%

Sigma-Aldrich

N2630

Nicotinamide 1,N6-ethenoadenine dinucleotide

Nicotinamide BioReagent, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich

N0636

Nicotinamide

Nicotinamide EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC

SAFC

5.00299

Nicotinamide

Industrial application of green chromatography?I. Separation and analysis of niacinamide in skincare creams using pure water as the mobile phase
Yang Y, et al.
Talanta, 84(1), 169-174 (2011)
Evaluation of analytical tools and multivariate methods for quantification of co-former crystals in ibuprofen-nicotinamide co-crystals
Soares FLF and Carneiro RL
Journal of Pharmaceutical and Biomedical Analysis, 89, 166-175 (2014)
Efrat Resnick et al.
Journal of the American Chemical Society, 141(22), 8951-8968 (2019-05-08)
Covalent probes can display unmatched potency, selectivity, and duration of action; however, their discovery is challenging. In principle, fragments that can irreversibly bind their target can overcome the low affinity that limits reversible fragment screening, but such electrophilic fragments were
Nicotinamide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 14(4), 3145-3146 (2017)
Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceuticals and biological fluids after solid phase extraction
Chatzimichalakis PF, et al.
Journal of Separation Science, 27(14), 1181-1188 (2004)
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Domande

1–2 di 2 domande  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

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