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S1650

Sigma-Aldrich

Seleno-DL-cystine

>98% (TLC), suitable for HPLC

Sinonimo/i:

3,3′-diselenobis- alanine,

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About This Item

Formula empirica (notazione di Hill):
C6H12N2O4Se2
Numero CAS:
2897-21-4
Peso molecolare:
334.09
Numero MDL:
MFCD00055925
Codice UNSPSC:
12352209
ID PubChem:
24899489
NACRES:
NA.26

product name

Seleno-DL-cystine, powder

Saggio

>98% (TLC)

Forma fisica

powder

tecniche

HPLC: suitable

Punto di fusione

222 °C

Temperatura di conservazione

−20°C

Stringa SMILE

NC(C[Se][Se]CC(N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)
JULROCUWKLNBSN-UHFFFAOYSA-N

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Categorie correlate

Avvertenze

Danger

Indicazioni di pericolo

H301 + H331,H373,H410

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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DL-Cysteine technical grade

Sigma-Aldrich

861677

DL-Cysteine

DL-Methionine European Pharmacopoeia (EP) Reference Standard

M0950000

DL-Methionine

Dimethyl diselenide 96%

Sigma-Aldrich

328502

Dimethyl diselenide

L-Selenomethionine-(methyl-13C) 99 atom % 13C

Sigma-Aldrich

634093

L-Selenomethionine-(methyl-13C)

N-(Phenylseleno)phthalimide technical grade

Sigma-Aldrich

254614

N-(Phenylseleno)phthalimide

L-Homocysteic acid ≥95%

Sigma-Aldrich

H9633

L-Homocysteic acid

Pierre Burguière et al.
Journal of bacteriology, 186(15), 4875-4884 (2004-07-21)
The symporter YhcL and two ATP binding cassette transporters, YtmJKLMN and YckKJI, were shown to mediate L-cystine uptake in Bacillus subtilis. A triple DeltayhcL DeltaytmJKLMN DeltayckK mutant was unable to grow in the presence of L-cystine and to take up
Amit Kunwar et al.
Radiation and environmental biophysics, 50(2), 271-280 (2011-01-25)
Selenocystine (CysSeSeCys), a diselenide aminoacid exhibiting glutathione peroxidase-like activity and selective antitumor effects, was examined for in vivo antigenotoxic and antioxidant activity in Swiss albino mice after exposure to a sublethal dose (5 Gy) of γ-radiation. For this, CysSeSeCys was administered
Eric Olm et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(27), 11400-11405 (2009-06-25)
The selenium salt selenite (SeO(3)(2-)) is cytotoxic in low to moderate concentrations, with a remarkable specificity for cancer cells resistant to conventional chemotherapy. Our data show that selenium uptake and accumulation, rather than intracellular events, are crucial to the specific
Tianfeng Chen et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 63(2), 105-113 (2008-05-31)
Epidemiological and clinical studies have demonstrated that dietary supplementation of selenium (Se) could reduce the incidence of human cancers. In this study, selenocystine, a nutritionally available selenoamino acid, was identified as a novel agent with broad-spectrum antitumor activity. A panel
Tianfeng Chen et al.
The international journal of biochemistry & cell biology, 41(3), 666-676 (2008-08-23)
The role of selenium as potential cancer chemopreventive and chemotherapeutic agents has been supported by epidemiological, preclinical and clinical studies. Although cell apoptosis has been evidenced as a critical mechanism mediating the anticancer activity of selenium, the underlying molecular mechanisms
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