Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
MAK099
Glutamate Dehydrogenase (GDH) Activity Assay Kit
sufficient for 100 colorimetric tests
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Codice UNSPSC:
12161503
NACRES:
NA.84
Prodotti consigliati
impiego
sufficient for 100 colorimetric tests
Metodo di rivelazione
colorimetric
Malattie correlate
cancer; gastrointestinal diseases
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... GLUD1(2746) , GLUD2(2747)
mouse ... GLUD1(14661)
rat ... GLUD1(24399)
Descrizione generale
Glutamate Dehydrogenase (GDH) is a mitochondrial enzyme that catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate and serves as a key link between anabolic and catabolic pathways. In mammals, GDH is subject to allosteric regulation and has high activity in liver, kidney, brain, and pancreas.[1] GDH activity in serum can be used to differentiate between liver diseases due to liver inflammation, which do not show elevated serum GDH activity, and diseases that result in hepatocyte necrosis, which results in elevated serum GDH.[2]
Applicazioni
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Compatibilità
Suitable for detecting glutamate dehydrogenase (GDH) activity in serum or tissue and cell extracts.
Principio
GDH activity is determined by a coupled enzyme assay in which glutamate is consumed by GDH generating NADH, which reacts with a probe generating a colorimetric (450 nm) product proportional to the GDH activity present. One unit of GDH is the amount of enzyme that will generate 1.0 μmole of NADH per minute at pH 7.6 at 37 °C.
Sostituito da
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
10 - Combustible liquids
Scegli una delle versioni più recenti:
Certificati d'analisi (COA)
Lot/Batch Number
Non trovi la versione di tuo interesse?
Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
The glutamate dehydrogenase pathway and its roles in cell and tissue biology in health and disease.
Plaitakis A, et al.
Biology, 6(1), 11-11 (2017)
Is liver enzyme release really associated with cell necrosis induced by oxidant stress?.
Contreras-Zentella M L and Hernandez-Mu?oz R
Oxidative Medicine and Cellular Longevity, 2016 (2016)
Tongxin Wang et al.
Animal nutrition (Zhongguo xu mu shou yi xue hui), 4(3), 329-337 (2018-09-04)
The liver is the most essential organ for the metabolism of ammonia, in where most of ammonia is removed by urea and glutamine synthesis. Regulated by leucine, glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to ammonia. To determine
Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.
Castex J, et al.
Cell Death & Disease, 8(2), e2631-e2631 (2017)
David Papadopoli et al.
Neoplasia (New York, N.Y.), 23(4), 391-399 (2021-03-31)
Notwithstanding that high rates of glucose uptake and glycolysis are common in neoplasia, pharmacological efforts to inhibit glucose utilization for cancer treatment have not been successful. Recent evidence suggests that in addition to classical glucose transporters, sodium-glucose transporters (SGLTs) are
-
What is the Department of Transportation shipping information for this product?
1 risposta-
Utile?
-
Filtri attivi
Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.
