G4256
Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast
Type IV, lyophilized powder, 20-60 units/mg protein (modified Warburg-Christian)
Sinonimo/i:
GALT, UDP glucose:α-D-galactose-1-phosphate uridyltransferase
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20 UNITS
769,00 €
50 UNITS
1.530,00 €
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Cambia visualizzazione
20 UNITS
769,00 €
50 UNITS
1.530,00 €
About This Item
Numero CAS:
Numero MDL:
Codice UNSPSC:
12352204
NACRES:
NA.54
Prodotti consigliati
Tipo
Type IV
Livello qualitativo
Stato
lyophilized powder
Attività specifica
20-60 units/mg protein (modified Warburg-Christian)
Composizione
Protein, 15-35%
Attività estranea
6-phosphogluconate dehydrogenase ≤0.5%
UDP glucose pyrophosphorylase and galactokinase ≤0.2%
Temperatura di conservazione
−20°C
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Descrizione generale
Research area: Cell Signaling
Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.[1] GALT gene is mapped to human chromosome 9p13.[2] Deficiency of GALT results in type 1 galactosemia.[1]
Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.[1] GALT gene is mapped to human chromosome 9p13.[2] Deficiency of GALT results in type 1 galactosemia.[1]
Applicazioni
Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast has been used to perform enzyme assays.
Definizione di unità
One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25 °C as detected by a coupled system using phosphoglucomutase.
Stato fisico
Contains buffer salts as citrate and reduced glutathione
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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All monodeoxygenated galactoses were treated with galactokinase, and for the 2-, 3-, and 4-deoxy compounds, transformation into the corresponding galactopyranosyl phosphates could be observed. In case of the 2-deoxy derivative, further reaction via UDP-2-deoxy-D-lyxo-hexose (UDP-2-deoxygalactose), which was also obtained chemically
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Journal of inherited metabolic disease, 32(3), 412-415 (2009-05-07)
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The Cucurbitaceae translocate a significant portion of their photosynthate as raffinose and stachyose, which are galactosyl derivatives of sucrose. These are initially hydrolyzed by alpha-galactosidase to yield free galactose (Gal) and, accordingly, Gal metabolism is an important pathway in Cucurbitaceae
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REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are unclear and the consequences of the presence of two related proteins are
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Journal francais d'ophtalmologie, 28(5), 490-496 (2005-06-25)
Galactosemia is an inherited metabolic disorder due to a defect in one of the three enzymes required to fully metabolize the galactose in glucose: the galactose 1-phosphate uridyltransferase. Because this enzyme is present in the normal foetal liver since the
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