E6510

Ergosterol

≥75%

• Sinonimo/i: 3β-Hydroxy-5,7,22-ergostatriene, 5,7,22-Ergostatrien-3β-ol, Provitamin D₂
• Formula empirica (notazione di Hill): C₂₈H₄₄O
• Numero CAS: 57-87-4
• Peso molecolare: 396.65
• Beilstein: 2338604
• Numero CE: 200-352-7
• Numero MDL: MFCD00003623
• Codice UNSPSC: 12352205
• ID PubChem: 24894628
• NACRES: NA.77

Proprietà

• Origine biologica: microbial
• Livello qualitativo: 100
• Saggio: ≥75%
• Stato: powder
• Colore: white to off-white
• Punto di fusione: 156-158 °C (lit.)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
• InChI: 1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1; DNVPQKQSNYMLRS-APGDWVJJSA-N

Descrizione

Descrizione generale

Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes.[1]

Applicazioni

Ergosterol has been used:

• as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers[2]
• as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol[3]
• as a component of the culture medium to isolate the CYP51^RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis[4]

Azioni biochim/fisiol

Ergosterol has a role in maintaining the integrity of the cell membrane[5] and its fluidity.[6] The sterol has anti-tumor and anti-inflammatory properties.[7]

Informazioni sulla sicurezza

• Indicazioni di pericolo: H413
• Consigli di prudenza: P273
• Classi di pericolo: Aquatic Chronic 4
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges