This product is not sterile. Prepared solutions may be filter sterilized.
D0627
N6,2′-O-Dibutirril-adenosina 3′,5′-ciclica monofosfato
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
≥96% (HPLC), powder
Sinonimo/i:
AMP ciclico dibutirrile, Bucladesina, cAMP dibutirrile
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25 MG
85,50 €
100 MG
270,00 €
250 MG
455,00 €
1 G
1.340,00 €
5 X 1 G
5.360,00 €
Scegli un formato
Cambia visualizzazione
25 MG
85,50 €
100 MG
270,00 €
250 MG
455,00 €
1 G
1.340,00 €
5 X 1 G
5.360,00 €
About This Item
Formula condensata:
C18H23N5O8PNa
Numero CAS:
Peso molecolare:
491.37
Numero CE:
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51
Prodotti consigliati
Origine biologica
synthetic (organic)
Livello qualitativo
Saggio
≥96% (HPLC)
Stato
powder
Impurezze
≤0.5% Cyclic AMP
≤3% monobutyryl derivatives
Colore
off-white
Solubilità
H2O: 100 mg/mL
Temperatura di conservazione
−20°C
Stringa SMILE
[Na+].CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3OC(=O)CCC
InChI
1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1
KRBZRVBLIUDQNG-JBVYASIDSA-M
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Applicazioni
Il di-butirril cAMP è un analogo del cAMP cellule-permeabile in grado di attivare la protein-chinasi cAMP dipendente (PKA) o la via del segnale cAMP/PKA. Il di-butirril cAMP è usato come induttore di differenziazione morfologica e modulatore della segnalazione cellulare in cellule come quelle di Schwann . Dibutyrl cAMP is used in a variety of differentiation studies, such as neuron differentiation / neuronal differentiation.
Azioni biochim/fisiol
Analogo cAMP permeabile alle cellule che attiva la chinasi proteica dipendente da cAMP (PKA).
Avvertenza
Perde il gruppo 2′-O-butirrile a pH 8,5
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Protocolli
Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.
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is this product sterile?
1 risposta-
Utile?
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How long is it stable in -20ºC after reconstitution in DMSO or H2O at 200mM? Do you have any recommendations for stability once the product is in solution?
1 risposta-
This product is soluble in water at 100 mg/mL. The solubility in DMSO has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months or refrigerate at 2 - 8°C for up to 3 days. Avoid pH of 8.5 or greater as hydrolysis will occur. Please see the link below to review the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/368/353/d0627pis-ms.pdfUtile?
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